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  3. Dr. José Miguel Domínguez Ruiz-Tagle
Dr. José Miguel Domínguez Ruiz-Tagle

Dr. José Miguel Domínguez Ruiz-Tagle

Profesor Asistente

ÁREA DE INTERÉS

  • Cáncer de tiroides - Nódulos tiroideos

 

FORMACIÓN
- Pregrado: Pontificia Universidad Católica de Chile

  • 1995 - 2001: Título de Médico-Cirujano o correspondiente

- Postgrado:

  • 2002 - 2005: Especialista en Medicina Interna, Universidad de Chile
  • 2007 - 2009: Especialista en Endocrinología, Pontificia Universidad Católica de Chile
  • 2010 - 2012: Especialista en Cáncer de Tiroides, Memorial Sloan Kettering Cancer Center, Nueva York, Estadis Unidos

 

PUBLICACIONES

  1. Warthin-like and classic papillary thyroid cancer have similar clinical presentation and prognosis.
    Olmos R, Muñoz F, Donoso F, López J, Bruera MJ, Ruiz-Esquide M, Mosso L, Lustig N, Solar A, Droppelmann N, Montero PH, González HE, Domínguez JM. Arch Endocrinol Metab. 2020 Jun 29:S2359-39972020005004206. doi: 10.20945/2359-3997000000270. Online ahead of print
  2. Manejo de nódulos tiroideos y cáncer de tiroides con lobectomía: experiencia de un equipo multidisciplinario
    Olmos R, López J, Donoso J, Ruiz-Esquide M, Zegers T, Mosso L,Lustig N, Domínguez F, Droppelmann N, González HE, Solar A, Cruz F, Montero PH, Domínguez JM. Rev Chil Endo Diab 2020; 13(3): 118-124
  3. Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer. Ho AL, Grewal RK, Leboeuf R, Sherman EJ, Pfister DG, Deandreis D, Pentlow KS, Zanzonico PB, Haque S, Gavane S, Ghossein RA, Ricarte-Filho JC, Domínguez JM, Shen R, Tuttle RM, Larson SM, Fagin JA.
    N Engl J Med. 2013 Feb 14;368(7):623-32. doi: 10.1056/NEJMoa1209288.
  4. Thyroid nodules with indeterminate cytology. Domínguez JM. N Engl J Med. 2012 Nov 15;367(20):1958; author reply 1958-9. doi: 10.1056/NEJMc1211421.
  5. A Thyroid Genetic Classifier Correctly Predicts Benign Nodules with Indeterminate Cytology: Two Independent, Multicenter, Prospective Validation Trials. Zafereo M, McIver B, Vargas-Salas S, Domínguez JM, Steward DL, Holsinger FC, Kandil E, Williams M, Cruz F, Loyola S, Solar A, Roa JC, León A, Droppelman N, Lobos M, Arias T, Kong CS, Busaidy N, Grubbs EG, Graham P, Stewart J, Tang A, Wang J, Orloff L, Henríquez M, Lagos M, Osorio M, Schachter D, Franco C, Medina F, Wohllk N, Diaz RE, Veliz J, Horvath E, Tala H, Pineda P, Arroyo P, Vasquez F, Traipe E, Marín L, Miranda G, Bruce E, Bracamonte M, Mena N, González HE. Thyroid. 2020 May;30(5):704-712. doi: 10.1089/thy.2019.0490. Epub 2020 Feb 11.
  6. In properly selected patients with differentiated thyroid cancer, antithyroglobulin antibodies decline after thyroidectomy and their sole presence should not be an indication for radioiodine ablation. Zavala LF, Barra MI, Olmos R, Tuttle M, González H, Droppelmann N, Mosso L, Domínguez JM. Arch Endocrinol Metab. 2019 May-Jun;63(3):293-299. doi: 10.20945/2359-3997000000123. Epub 2019 Apr 25.
  7. The Combination of RET, BRAF and Demographic Data Identifies Subsets of Patients with Aggressive Papillary Thyroid Cancer. Martínez JRW, Vargas-Salas S, Gamboa SU, Muñoz E, Domínguez JM, León A, Droppelmann N, Solar A, Zafereo M, Holsinger FC, González HE. Horm Cancer. 2019 Jun;10(2-3):97-106. doi: 10.1007/s12672-019-0359-8. Epub 2019 Mar 22.
  8. Genetic testing for indeterminate thyroid cytology: review and meta-analysis. Vargas-Salas S, Martínez JR, Urra S, Domínguez JM, Mena N, Uslar T, Lagos M, Henríquez M, González HE. Endocr Relat Cancer. 2018 Mar;25(3):R163-R177. doi: 10.1530/ERC-17-0405. Epub 2017 Dec 18.
  9. Neck Sonography and Suppressed Thyroglobulin Have High Sensitivity for Identifying Recurrent/Persistent Disease in Patients With Low-risk Thyroid Cancer Treated With Total Thyroidectomy and Radioactive Iodine Ablation, Making Stimulated Thyroglobulin Unnecessary. Domínguez JM, Nilo F, Contreras T, Carmona R, Droppelmann N, González H, Iturrieta V, Tuttle RM. J Ultrasound Med. 2017 Nov;36(11):2299-2307. doi: 10.1002/jum.14260. Epub 2017 May 24.
  10. Papillary thyroid microcarcinoma: characteristics at presentation, and evaluation of clinical and histological features associated with a worse prognosis in a Latin American cohort. Domínguez JM, Nilo F, Martínez MT, Massardo JM, Muñoz S, Contreras T, Carmona R, Jerez J, González H, Droppelmann N, León A. Arch Endocrinol Metab. 2018 Feb;62(1):6-13. doi: 10.20945/2359-3997000000013.
  11. Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas. Montero-Conde C, Ruiz-Llorente S, Dominguez JM, Knauf JA, Viale A, Sherman EJ, Ryder M, Ghossein RA, Rosen N, Fagin JA. Cancer Discov. 2013 May;3(5):520-33. doi: 10.1158/2159-8290.CD-12-0531. Epub 2013 Jan 29.
  12. Suspicious cervical lymph nodes detected after thyroidectomy for papillary thyroid cancer usually remain stable over years in properly selected patients. Robenshtok E, Fish S, Bach A, Domínguez JM, Shaha A, Tuttle RM. J Clin Endocrinol Metab. 2012 Aug;97(8):2706-13. doi: 10.1210/jc.2012-1553. Epub 2012 May 25.
  13. Clinical outcomes and molecular profile of differentiated thyroid cancers with radioiodine-avid distant metastases. Sabra MM, Dominguez JM, Grewal RK, Larson SM, Ghossein RA, Tuttle RM, Fagin JA. J Clin Endocrinol Metab. 2013 May;98(5):E829-36. doi: 10.1210/jc.2012-3933. Epub 2013 Mar 26
  14. Switch in signaling control of mTORC1 activity after oncoprotein expression in thyroid cancer cell lines. Malaguarnera R, Chen KY, Kim TY, Dominguez JM, Voza F, Ouyang B, Vundavalli SK, Knauf JA, Fagin JA. J Clin Endocrinol Metab. 2014 Oct;99(10):E1976-87. doi: 10.1210/jc.2013-3976. Epub 2014 Jul 16.
  15. Risk of recurrence in differentiated thyroid cancer. Domínguez JM, Martínez MT, Massardo JM, Muñoz S, Droppelmann N, González HE, Mosso L. Rev Med Chil. 2018 Mar;146(3):282-289. doi: 10.4067/s0034-98872018000300282.
  16. From macro to micro thyroid carcinoma: records of a clinical hospital from 1991 to 2010. Mosso L, Campusano C, González H, Domínguez JM, Salman P, Suazo V, Solar A, Cerda J. Rev Med Chil. 2013 Apr;141(4):442-8. doi: 10.4067/S0034-98872013000400004.
  17. Papillary thyroid carcinoma presenting with pancreatic metastases. Report of one case. Uslar T, Chahuán J, Olmos R, Rodríguez C, Astudillo R, Zoroquiain P, Solar A, Espino A, León A, Fardella C, Dom

 

CAPÍTULOS DE LIBROS

  • 2015 : Dominguez JM, Pineda P. Patología Tiroidea en la Mujer", en Endocrinologia Ginecologica, Editor Dr. Eugenio Arteaga. Editorial Mediaterráneo, ISBN: 978-956-220-381-4
  • 2018 : Coeditor del libro Endocrinologia Clinica. Arteaga E, Baudrand R, Dominguez JM., editores. Editorial Mediterraneo. ISBN 978-956-220-402-6
  • 2018: Dominguez JM. "Aproximacion al paciente con patologia tiroidea", en Endocrinologia Clinica, Editores Arteaga E, Baudrand R, Dominguez JM. Editorial Mediterraneo. ISBN 978-956-220-402-6
  • 2018 : Dominguez JM. "Nodulo tiroideo", en Endocrinologia Clinica, Editores Arteaga E, Baudrand R, Dominguez JM. Editorial Mediterraneo. ISBN 978-956-220-402-6
  • 2018 : Dominguez JM, Tala H. Cancer diferenciado de Tiroides", en Endocrinologia Clinica, Editores Arteaga E, Baudrand R, Dominguez JM. Editorial Mediterraneo. ISBN 978-956-220-402-6
  • 2018 : Baudrand R, Campusano C, Mosso L, Dominguez JM. "Patologia endocrinologica en el embarazo", en Endocrinologia Clinica, Editores Arteaga E, Baudrand R, Dominguez JM. Editorial Mediterraneo. ISBN 978-956-220-402-6

 

PREMIOS Y DISTINCIONES

  • 2005: Mejor becado de Medicina Interna, Hospital del Salvador

 

PROYECTOS DE INVESTIGACIÓN ACTIVOS

  • Seguimiento de Pacientes con Cáncer de Tiroides

 

MEMBRESÍA SOCIEDADES CIENTIFICAS

  • Sociedad Chilena de Endocrinología y Diabetes
  • Sociedad Latinoamericana de Tiroides